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  • Flag_icon When is early intervention with an AAF recommended?
  • MONITORING MICRONUTRIENTS IN CHILDREN WITH COMPLEX,
    MULTIPLE DIAGNOSES ON AMINO ACID FORMULAS (AAF)

    Children who are commenced on AAFs require regular monitoring and review and follow up is essential to ensure they receive adequate nutrition.1 AAFs are formulated to be nutritionally complete and in line with Foods for Special Medical Purposes (FSMP) legislation. However, it is important to regularly check nutritional status, as requirements can change (e.g. with changes in clinical condition). Monitoring can include a review of nutritional intake and requirements, anthropometry, assessment of symptoms and micronutrient status1. This document focuses only on micronutrient monitoring of children who are receiving an AAF as a sole source of nutrition who have complex, multiple diagnoses.


    Why should these children be monitored?

    • Children with complex systemic disease involving multiple diagnoses and intestinal disease may have increased micronutrient losses, a reduced absorptive capacity and/or higher micronutrient demands impacting micronutrient status.2,3,4
    • It can be difficult to establish the micronutrient status of a child through dietary assessment alone and so reliable blood markers can be helpful.5

    What micronutrients should be monitored?


    Micro Nutrients


    Monitoring may be required earlier or more frequently where there is a clinical concern, or with children that are likely to have/with known unstable micronutrient profiles.

    Serum levels of micronutrients, particularly phosphorus, should be routinely monitored by clinicians when Neocate is used as a primary or sole source of nutrition for patients with complex systemic disease involving multiple diagnoses and intestinal disease,* especially in combination with tube feeding and/or a history of prematurity. Neocate** formulas are intended for use under medical supervision.


    * A retrospective review identified case studies of patients on primary or sole source nutrition with diagnoses covering multiple systems, including congenital gastrointestinal anomalies and GI surgeries (such as necrotizing enterocolitis, esophageal atresia, tracheoesophageal fistula); neurological conditions (such as seizures, intraventricular hemorrhage, hydrocephalus); respiratory (lung disease, tracheostomy, aspiration); cardiac (congenital heart disease); and other systemic conditions, often in conjunction with tube feeding and/or a history of prematurity2.


    ** Neocate is an amino acid-based formula for the dietary management of cow’s milk allergy, multiple food protein allergies and other conditions where an amino acid diet is recommended.

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